Ontology highlight
ABSTRACT:
SUBMITTER: Cai F
PROVIDER: S-EPMC3216402 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Cai Feng F Pu Xiaotao X Qi Xiangbing X Lynch Vincent V Radha Akella A Ready Joseph M JM
Journal of the American Chemical Society 20111021 45
We demonstrate that allenes, chiral 1,2-dienes, appended with basic functionality can serve as ligands for transition metals. We describe an allene-containing bisphosphine that, when coordinated to Rh(I), promotes the asymmetric addition of arylboronic acids to α-keto esters with high enantioselectivity. Solution and solid-state structural analysis reveals that one olefin of the allene can coordinate to transition metals, generating bi- and tridentate ligands. ...[more]