Ontology highlight
ABSTRACT:
SUBMITTER: Madden MM
PROVIDER: S-EPMC2765658 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Madden Michael M MM Rivera Vera Claudia I CI Song Wenjiao W Lin Qing Q
Chemical communications (Cambridge, England) 20090813 37
We report the first use of a photoinduced 1,3-dipolar cycloaddition reaction in "stapling" peptide sidechains to reinforce a model peptide helical structure with moderate to excellent yields; the resulting pyrazoline "staplers" exhibit unique fluorescence useful in a cell permeability study. ...[more]