Ontology highlight
ABSTRACT:
SUBMITTER: Brawn RA
PROVIDER: S-EPMC3164318 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Organic letters 20100101 2
Enantioenriched allenylsilanes are used in three-component propargylation reactions with aldehydes and silyl ethers to form syn-homopropargylic ethers that contain an imbedded azide. These materials then undergo thermally induced intramolecular 1,3-dipolar cycloaddition reactions, resulting in unique fused ring systems containing 1,2,3-triazoles. The ability to modify all three components of the reaction allows for expedient access to compounds containing significant structural and stereochemica ...[more]