Ontology highlight
ABSTRACT:
SUBMITTER: Fontanes V
PROVIDER: S-EPMC2767405 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Fontanes Vanessa V Raychaudhuri Santanu S Dasgupta Asim A
Virology 20090908 1
Hepatitis C virus (HCV) infection frequently leads to chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. There is no effective therapy or vaccine available to HCV-infected patients other than interferon-ribavarin combination, which is effective in a relatively small percentage of infected patients. Our previous results have shown that a synthetic peptide (LAP) corresponding to the N-terminal 18 amino acids of the Lupus autoantigen (La) was a potent inhibitor of HCV IRES-mediated t ...[more]