Ontology highlight
ABSTRACT:
SUBMITTER: Guan X
PROVIDER: S-EPMC2771032 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Guan Xiaoxiang X Zhao Hui H Niu Jiangong J Tang Dongfeng D Ajani Jaffer A JA Wei Qingyi Q
BMC gastroenterology 20091016
<h4>Background</h4>Both TGF-beta1 and VEGF play a critic role in the multiple-step process of tumorgenesis of gastric cancer. Single nucleotide polymorphisms (SNPs) of the TGFB1 and VEGF genes have been associated with risk and progression of many cancers. In this study, we investigated the association between potentially functional SNPs of these two genes and risk of gastric cancer in a US population.<h4>Methods</h4>The risk associated with genotypes and haplotypes of four TGFB1 SNPs and four V ...[more]