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ABSTRACT:
SUBMITTER: Vuong TV
PROVIDER: S-EPMC2772456 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Applied and environmental microbiology 20090904 21
A relationship between processivity and synergism has not been reported for cellulases, although both characteristics are very important for hydrolysis of insoluble substrates. Mutation of two residues located in the active site tunnel of Thermobifida fusca exocellulase Cel6B increased processivity on filter paper. Surprisingly, mixtures of the Cel6B mutant enzymes and T. fusca endocellulase Cel5A did not show increased synergism or processivity, and the mutant enzyme which had the highest proce ...[more]