Molecular characterization of the phenylacetic acid catabolic pathway in Pseudomonas putida U: the phenylacetyl-CoA catabolon.
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ABSTRACT:
SUBMITTER: Olivera ER
PROVIDER: S-EPMC27761 | biostudies-literature | 1998 May
REPOSITORIES: biostudies-literature
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Molecular characterization of the phenylacetic acid catabolic pathway in Pseudomonas putida U: the phenylacetyl-CoA catabolon.
Olivera E R ER Miñambres B B García B B Muñiz C C Moreno M A MA Ferrández A A Díaz E E García J L JL Luengo J M JM
Proceedings of the National Academy of Sciences of the United States of America 19980501 11
Fourteen different genes included in a DNA fragment of 18 kb are involved in the aerobic degradation of phenylacetic acid by Pseudomonas putida U. This catabolic pathway appears to be organized in three contiguous operons that contain the following functional units: (i) a transport system, (ii) a phenylacetic acid activating enzyme, (iii) a ring-hydroxylation complex, (iv) a ring-opening protein, (v) a beta-oxidation-like system, and (vi) two regulatory genes. This pathway constitutes the common ...[more]
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