Ontology highlight
ABSTRACT:
SUBMITTER: Leak TS
PROVIDER: S-EPMC2778056 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Leak T S TS Perlegas P S PS Smith S G SG Keene K L KL Hicks P J PJ Langefeld C D CD Mychaleckyj J C JC Rich S S SS Kirk J K JK Freedman B I BI Bowden D W DW Sale M M MM
Annals of human genetics 20090123 2
Variants in the engulfment and cell motility 1 (ELMO1) gene are associated with nephropathy due to type 2 diabetes mellitus (T2DM) in a Japanese cohort. We comprehensively evaluated this gene in African American (AA) T2DM patients with end-stage renal disease (ESRD). Three hundred and nine HapMap tagging SNPs and 9 reportedly associated SNPs were genotyped in 577 AA T2DM-ESRD patients and 596 AA non-diabetic controls, plus 43 non-diabetic European American controls and 45 Yoruba Nigerian samples ...[more]