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PathBuilder--open source software for annotating and developing pathway resources.


ABSTRACT:

Summary

We have developed PathBuilder, an open-source web application to annotate biological information pertaining to signaling pathways and to create web-based pathway resources. PathBuilder enables annotation of molecular events including protein-protein interactions, enzyme-substrate relationships and protein translocation events either manually or through automated importing of data from other databases. Salient features of PathBuilder include automatic validation of data formats, built-in modules for visualization of pathways, automated import of data from other pathway resources, export of data in several standard data exchange formats and an application programming interface for retrieving existing pathway datasets.

Availability

PathBuilder is freely available for download at http://pathbuilder.sourceforge.net/ under the terms of GNU lesser general public license (LGPL: http://www.gnu.org/copyleft/lesser.html). The software is platform independent and has been tested on Windows and Linux platforms.

Contact

pandey@jhmi.edu

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Kandasamy K 

PROVIDER: S-EPMC2781757 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature

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Publications

PathBuilder--open source software for annotating and developing pathway resources.

Kandasamy Kumaran K   Keerthikumar Shivakumar S   Raju Rajesh R   Keshava Prasad T S TS   Ramachandra Y L YL   Mohan Sujatha S   Pandey Akhilesh A  

Bioinformatics (Oxford, England) 20090723 21


<h4>Summary</h4>We have developed PathBuilder, an open-source web application to annotate biological information pertaining to signaling pathways and to create web-based pathway resources. PathBuilder enables annotation of molecular events including protein-protein interactions, enzyme-substrate relationships and protein translocation events either manually or through automated importing of data from other databases. Salient features of PathBuilder include automatic validation of data formats, b  ...[more]

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