Ontology highlight
ABSTRACT:
SUBMITTER: Lee SY
PROVIDER: S-EPMC2782199 | biostudies-literature | 2005 Jun
REPOSITORIES: biostudies-literature
Lee Sun Young SY Choi Moon Seok MS Lee Dongho D Lee Joon Hyoek JH Koh Kwang Cheol KC Paik Seung Woon SW Yoo Byung Chul BC
Journal of Korean medical science 20050601 3
Disappearance of hepatitis B surface antigens (HBsAg) in chronic hepatitis B usually indicates clearance of hepatitis B virus (HBV) infection. However, false HBsAg negativity with mutations in pre-S2 and 'a' determinant has been reported. It is also known that YMDD mutations decrease the production of HBV and escape detection of serum HBsAg. Here, we report overlapping gene mutations in a patient with HBsAg loss during the lamivudine therapy. After 36 months of lamivudine therapy in a 44-yrold K ...[more]