Ontology highlight
ABSTRACT:
SUBMITTER: Bickel PE
PROVIDER: S-EPMC2782626 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Bickel Perry E PE Tansey John T JT Welte Michael A MA
Biochimica et biophysica acta 20090416 6
The PAT family of lipid droplet proteins includes 5 members in mammals: perilipin, adipose differentiation-related protein (ADRP), tail-interacting protein of 47 kDa (TIP47), S3-12, and OXPAT. Members of this family are also present in evolutionarily distant organisms, including insects, slime molds and fungi. All PAT proteins share sequence similarity and the ability to bind intracellular lipid droplets, either constitutively or in response to metabolic stimuli, such as increased lipid flux int ...[more]