Ontology highlight
ABSTRACT:
SUBMITTER: Brubaker CE
PROVIDER: S-EPMC2783676 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Brubaker Carrie E CE Kissler Hermann H Wang Ling-Jia LJ Kaufman Dixon B DB Messersmith Phillip B PB
Biomaterials 20091006 3
There is significant need for effective medical adhesives that function reliably on wet tissue surfaces with minimal inflammatory insult. To address these performance characteristics, we have generated a synthetic adhesive biomaterial inspired by the protein glues of marine mussels. In-vivo performance was interrogated in a murine model of extrahepatic syngeneic islet transplantation, as an alternative to standard portal administration. The adhesive precursor polymer consisted of a branched poly ...[more]