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ABSTRACT:
SUBMITTER: Heuvingh J
PROVIDER: S-EPMC2785014 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Heuvingh Julien J Bonneau Stéphanie S
Biophysical journal 20091201 11
Oxidation of unsaturated lipids is a fundamental process involved in cell bioenergetics as well as in cell death. Using giant unilamellar vesicles and a chlorin photosensitizer, we asymmetrically oxidized the outer or inner monolayers of lipid membranes. We observed different shape transitions such as oblate to prolate and budding, which are typical of membrane curvature modifications. The asymmetry of the shape transitions is in accordance with a lowered effective spontaneous curvature of the l ...[more]