Ontology highlight
ABSTRACT:
SUBMITTER: Raposo G
PROVIDER: S-EPMC2786984 | biostudies-literature | 2007 Oct
REPOSITORIES: biostudies-literature
Raposo Graça G Marks Michael S MS
Nature reviews. Molecular cell biology 20071001 10
Melanosomes are tissue-specific lysosome-related organelles of pigment cells in which melanins are synthesized and stored. Analyses of the trafficking and fate of melanosomal components are beginning to reveal how melanosomes are formed through novel pathways from early endosomal intermediates. These studies unveil generalized structural and functional modifications of the endosomal system in specialized cells, and provide unexpected insights into the biogenesis of multivesicular bodies and how ...[more]