Ontology highlight
ABSTRACT:
SUBMITTER: Yang L
PROVIDER: S-EPMC2787497 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Yang Ling L He Jing J Huang Shuhong S Zhang Xiaoli X Bian Yuehong Y He Nonggao N Zhang Hongwei H Xie Jingwu J
Molecular cancer 20091127
The hedgehog (Hh) signaling pathway regulates many processes of development and tissue homeostasis. Activation of hedgehog signaling has been reported in about 30% of human cancer including ovarian cancer. Inhibition of hedgehog signaling has been pursued as an effective strategy for cancer treatment including an ongoing phase II clinical trial in ovarian cancer. However, the rate of hedgehog signaling activation in ovarian cancer was reported differently by different groups. To predict the succ ...[more]