Ontology highlight
ABSTRACT:
SUBMITTER: Nikiforovich GV
PROVIDER: S-EPMC2787753 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Nikiforovich Gregory V GV Baranski Thomas J TJ
Biochemical and biophysical research communications 20090930 3
The study presents structural models for the complex of the chemotaxis inhibitory protein of Staphylococcus aureus, CHIPS, and receptor for anaphylotoxin C5a, C5aR. The models are based on the recently found NMR structure of the complex between CHIPS fragment 31-121 and C5aR fragment 7-28, as well as on previous results of molecular modeling of C5aR. Simple and straightforward modeling procedure selected low-energy conformations of the C5aR fragment 8-41 that simultaneously fit the NMR structure ...[more]