Ontology highlight
ABSTRACT:
SUBMITTER: Pregizer S
PROVIDER: S-EPMC2787762 | biostudies-literature | 2009 Oct-Dec
REPOSITORIES: biostudies-literature
Pregizer Steven S Mortlock Douglas P DP
Cytokine & growth factor reviews 20091001 5-6
Much evidence suggests that "developmental regulator" genes, like those encoding transcription factors and signaling molecules, are typically controlled by many modular, tissue-specific cis-regulatory elements that function during embryogenesis. These elements are often far from gene coding regions and promoters. Bone morphogenetic proteins (BMPs) drive many processes in development relating to organogenesis and differentiation. Four BMP family members, Bmp2, Bmp4, Bmp5, and Gdf6, are now known ...[more]