Ontology highlight
ABSTRACT:
SUBMITTER: Rhee S
PROVIDER: S-EPMC2787981 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Experimental cell research 20090929 2
Three-dimensional (3D) cell-matrix cultures provide a useful model to analyze and dissect the structural, functional, and mechanical aspects of cell-matrix interactions and motile behavior important for cell and tissue morphogenesis. In the current studies we tested the effects of serum and physiological growth factors on the morphogenetic behavior of human fibroblasts cultured on the surfaces of 3D collagen matrices. Fibroblasts in medium containing serum contracted into clusters, whereas cells ...[more]