Ontology highlight
ABSTRACT:
SUBMITTER: Feldman KS
PROVIDER: S-EPMC2789421 | biostudies-literature | 2005 Nov
REPOSITORIES: biostudies-literature
Feldman Ken S KS Eastman Kyle J KJ
Journal of the American Chemical Society 20051101 44
Treatment of the representative diazoparaquinone prekinamycin dimethyl ether with Bu3SnH/AIBN in aromatic solvents furnishes moderate-to-good yields of formal aryl adducts wherein a molecule of solvent is attached to the carbon (C(11)) previously bearing the diazo function. Substituent studies provide evidence in support of a radical aromatic substitution mechanism, in which radical addition to the diazoparaquinone function generates an intermediate C(11) vinylic radical. ...[more]