Ontology highlight
ABSTRACT:
SUBMITTER: Lin FM
PROVIDER: S-EPMC2789940 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Lin Feng-Ming FM Lai Yi-Ju YJ Shen Hui-Ju HJ Cheng Yun-Hsin YH Wang Ting-Fang TF
The EMBO journal 20091203 3
The synaptonemal complex (SC) is a tripartite protein structure consisting of two parallel axial elements (AEs) and a central region. During meiosis, the SC connects paired homologous chromosomes, promoting interhomologue (IH) recombination. Here, we report that, like the CE component Zip1, Saccharomyces cerevisiae axial-element structural protein, Red1, can bind small ubiquitin-like modifier (SUMO) polymeric chains. The Red1-SUMO chain interaction is dispensable for the initiation of meiotic DN ...[more]