Ontology highlight
ABSTRACT:
SUBMITTER: Schridde U
PROVIDER: S-EPMC2790390 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Cerebral cortex (New York, N.Y. : 1991) 20071205 8
Blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) is widely used in neuroscience to study brain activity. However, BOLD fMRI does not measure neuronal activity directly but depends on cerebral blood flow (CBF), cerebral blood volume (CBV), and cerebral metabolic rate of oxygen (CMRO(2)) consumption. Using fMRI, CBV, CBF, neuronal recordings, and CMRO(2) modeling, we investigated how the signals are related during seizures in rats. We found that increases in hemodyn ...[more]