Ontology highlight
ABSTRACT:
SUBMITTER: Aksenov DP
PROVIDER: S-EPMC4635237 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Aksenov Daniil P DP Li Limin L Miller Michael J MJ Iordanescu Gheorghe G Wyrwicz Alice M AM
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20150624 11
Most functional magnetic resonance imaging (fMRI) animal studies rely on anesthesia, which can induce a variety of drug-dependent physiological changes, including depression of neuronal activity and cerebral metabolism as well as direct effects on the vasculature. The goal of this study was to characterize the effects of anesthesia on the BOLD signal and neuronal activity. Simultaneous fMRI and electrophysiology were used to measure changes in single units (SU), multi-unit activity (MUA), local ...[more]