Synthesis of (-)-berkelic acid.
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ABSTRACT:
SUBMITTER: Wu X
PROVIDER: S-EPMC2790819 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Publications
Synthesis of (-)-berkelic acid.
Wu Xiaoxing X Zhou Jingye J Snider Barry B BB
Angewandte Chemie (International ed. in English) 20090101 7
An extremophilic challenge: Stereospecific condensation of a fully functionalized ketal aldehyde and a 2,6-dihydroxybenzoic acid is the key step in the synthesis of (-)-berkelic acid confirming Fürstner's reassignment of the stereochemistry at C18 and C19, establishing the absolute stereochemistry, and tentatively assigning the stereochemistry at C22. ...[more]
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