Ontology highlight
ABSTRACT:
SUBMITTER: Yerges LM
PROVIDER: S-EPMC2791518 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Yerges Laura M LM Klei Lambertus L Cauley Jane A JA Roeder Kathryn K Kammerer Candace M CM Moffett Susan P SP Ensrud Kristine E KE Nestlerode Cara S CS Marshall Lynn M LM Hoffman Andrew R AR Lewis Cora C Lang Thomas F TF Barrett-Connor Elizabeth E Ferrell Robert E RE Orwoll Eric S ES Zmuda Joseph M JM
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20091201 12
Genetics is a well-established but poorly understood determinant of BMD. Whereas some genetic variants may influence BMD throughout the body, others may be skeletal site specific. We initially screened for associations between 4608 tagging and potentially functional single nucleotide polymorphisms (SNPs) in 383 candidate genes and femoral neck and lumbar spine volumetric BMD (vBMD) measured from QCT scans among 862 community-dwelling white men >or=65 yr of age in the Osteoporotic Fractures in Me ...[more]