Ontology highlight
ABSTRACT:
SUBMITTER: Moreno JL
PROVIDER: S-EPMC2792875 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Moreno José L JL Sealfon Stuart C SC González-Maeso Javier J
Cellular and molecular life sciences : CMLS 20090826 23
Schizophrenia is one of the most common mental illnesses, with hereditary and environmental factors important for its etiology. All antipsychotics have in common a high affinity for monoaminergic receptors. Whereas hallucinations and delusions usually respond to typical (haloperidol-like) and atypical (clozapine-like) monoaminergic antipsychotics, their efficacy in improving negative symptoms and cognitive deficits remains inadequate. In addition, devastating side effects are a common characteri ...[more]