Plasma PLTP activity is inversely associated with HDL-C levels.
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ABSTRACT:
SUBMITTER: Chen X
PROVIDER: S-EPMC2793253 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
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Plasma PLTP activity is inversely associated with HDL-C levels.
Chen Xueying X Sun Aijun A Mansoor Ather A Zou Yunzeng Y Ge Junbo J Lazar Jason M JM Jiang Xian-Cheng XC
Nutrition & metabolism 20091130
Phospholipid transfer protein (PLTP) is an important modulator of lipoprotein metabolism, including interparticle phospholipid transfer, remodeling of HDL, cholesterol and phospholipid efflux from peripheral tissues, and the production of hepatic VLDL. PLTP also plays an important role in inflammation and oxidative stress. Accordingly, PLTP has been implicated in the development of atherosclerosis. In this study, we evaluated the association between PLTP activity and lipoprotein metabolism in a ...[more]
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