Ontology highlight
ABSTRACT:
SUBMITTER: Do MT
PROVIDER: S-EPMC2794210 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
Do Michael Tri H MT Kang Shin H SH Xue Tian T Zhong Haining H Liao Hsi-Wen HW Bergles Dwight E DE Yau King-Wai KW
Nature 20081231 7227
A subset of retinal ganglion cells has recently been discovered to be intrinsically photosensitive, with melanopsin as the pigment. These cells project primarily to brain centres for non-image-forming visual functions such as the pupillary light reflex and circadian photoentrainment. How well they signal intrinsic light absorption to drive behaviour remains unclear. Here we report fundamental parameters governing their intrinsic light responses and associated spike generation. The membrane densi ...[more]