Ontology highlight
ABSTRACT:
SUBMITTER: Yea K
PROVIDER: S-EPMC2797153 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Yea Kyungmoo K Kim Jaeyoon J Yoon Jong Hyuk JH Kwon Taewan T Kim Jong Hyun JH Lee Byoung Dae BD Lee Hae-Jeong HJ Lee Seung Jae SJ Kim Jong-In JI Lee Taehoon G TG Baek Moon-Chang MC Park Ho Seon HS Park Kyong Soo KS Ohba Motoi M Suh Pann-Ghill PG Ryu Sung Ho SH
The Journal of biological chemistry 20091008 49
Glucose homeostasis is maintained by the orchestration of peripheral glucose utilization and hepatic glucose production, mainly by insulin. In this study, we found by utilizing a combined parallel chromatography mass profiling approach that lysophosphatidylcholine (LPC) regulates glucose levels. LPC was found to stimulate glucose uptake in 3T3-L1 adipocytes dose- and time-dependently, and this activity was found to be sensitive to variations in acyl chain lengths and to polar head group types in ...[more]