Ontology highlight
ABSTRACT:
SUBMITTER: Otting N
PROVIDER: S-EPMC2802488 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Otting Nel N Doxiadis Gaby G M GG Bontrop Ronald E RE
Immunogenetics 20091124 11-12
The major histocompatibility complex (MHC) class I B gene/allelic repertoire was investigated in a pedigreed population of cynomolgus macaques of mixed Indonesian/Malaysian origin. The Mafa-B alleles detected in this cohort are mostly specific for a given geographic area, and only a small number of alleles appears to be shared with other populations. This suggests the fast evolution of Mafa-B alleles due to adaptation to new environments. In contrast to humans, the B locus in Old World monkeys d ...[more]