Ontology highlight
ABSTRACT:
SUBMITTER: Fiori KW
PROVIDER: S-EPMC2805257 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Nature chemistry 20091101 8
While Nature excels at performing selective modifications of complex polyfunctional molecules through the use of tailoring enzymes, synthetic chemistry has lagged behind in this regard. In prior work, we have applied a biomimetic approach to this problem, developing small peptides to achieve various group transfer reactions on polyol substrates with high enantio- or regioselectivity. The utility of sulfonates as synthetic building blocks and the scarcity of direct, selective methods for their pr ...[more]