Ontology highlight
ABSTRACT:
SUBMITTER: Demonchy R
PROVIDER: S-EPMC2806587 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Demonchy Raphaël R Blisnick Thierry T Deprez Caroline C Toutirais Géraldine G Loussert Céline C Marande William W Grellier Philippe P Bastin Philippe P Kohl Linda L
The Journal of cell biology 20091123 5
Numerous eukaryote genome projects have uncovered a variety of kinesins of unknown function. The kinesin 9 family is limited to flagellated species. Our phylogenetic experiments revealed two subfamilies: KIF9A (including Chlamydomonas reinhardtii KLP1) and KIF9B (including human KIF6). The function of KIF9A and KIF9B was investigated in the protist Trypanosoma brucei that possesses a single motile flagellum. KIF9A and KIF9B are strongly associated with the cytoskeleton and are required for motil ...[more]