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The adenosine wedge: a new structural motif in ribosomal RNA.


ABSTRACT: Here, we present a new recurrent RNA arrangement, the so-called adenosine wedge (A-wedge), which is found in three places of the ribosomal RNA in both ribosomal subunits. The arrangement has a hierarchical structure, consisting of elements previously described as recurrent motifs, namely, the along-groove packing motif, the A-minor and the hook-turn. Within the A-wedge, these elements are involved in different types of cause-effect relationships, providing together for the particular tertiary structure of the motif.

SUBMITTER: Gagnon MG 

PROVIDER: S-EPMC2811666 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature

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The adenosine wedge: a new structural motif in ribosomal RNA.

Gagnon Matthieu G MG   Steinberg Sergey V SV  

RNA (New York, N.Y.) 20091228 2


Here, we present a new recurrent RNA arrangement, the so-called adenosine wedge (A-wedge), which is found in three places of the ribosomal RNA in both ribosomal subunits. The arrangement has a hierarchical structure, consisting of elements previously described as recurrent motifs, namely, the along-groove packing motif, the A-minor and the hook-turn. Within the A-wedge, these elements are involved in different types of cause-effect relationships, providing together for the particular tertiary st  ...[more]

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