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Long-term observation of subunit vaccine F1-rV270 against Yersinia pestis in mice.


ABSTRACT: Long-term protection and antibody response for the subunit vaccine F1-rV270 were determined by using the mouse model. Antibodies to F1 and rV270 were still detectable over a period of 518 days. The complete protection against lethal challenge of Yersinia pestis could be achieved up to day 518 after primary immunization.

SUBMITTER: Wang Z 

PROVIDER: S-EPMC2812077 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature

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Long-term observation of subunit vaccine F1-rV270 against Yersinia pestis in mice.

Wang Zuyun Z   Zhou Lei L   Qi Zhizhen Z   Zhang Qingwen Q   Dai Ruixia R   Yang Yonghai Y   Cui Baizhong B   Wang Hu H   Yang Ruifu R   Wang Xiaoyi X  

Clinical and vaccine immunology : CVI 20091125 1


Long-term protection and antibody response for the subunit vaccine F1-rV270 were determined by using the mouse model. Antibodies to F1 and rV270 were still detectable over a period of 518 days. The complete protection against lethal challenge of Yersinia pestis could be achieved up to day 518 after primary immunization. ...[more]

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