Ontology highlight
ABSTRACT:
SUBMITTER: Toni TA
PROVIDER: S-EPMC2812128 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Toni Thomas A TA Brenner Bluma G BG Asahchop Eugene L EL Ntemgwa Michel M Moisi Daniella D Wainberg Mark A MA
Antimicrobial agents and chemotherapy 20091207 2
The selection of drug-resistant variants of human immunodeficiency virus type 1 (HIV-1) is an impediment to the efficiency of antiretroviral (ARV) therapy. We have developed an allele-specific real-time PCR assay to explore the presence of K65R minority species among treated HIV-1 subtype B and C infections. Thirty HIV-1 subtype C- and 26 subtype B-infected patients lacking K65R as determined by conventional sequencing methods were studied, and viral minority species were found in four HIV-1 sub ...[more]