Ontology highlight
ABSTRACT:
SUBMITTER: Carlson HK
PROVIDER: S-EPMC2812668 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Analytical biochemistry 20091009 2
Histidine-aspartic acid phosphotransfer pathways are central components of prokaryotic signal transduction pathways and are also found in many eukaryotes. Tools to study histidine kinases, however, are currently quite limited. In this article, we present a new tool to study histidine-aspartic acid phosphotransfer pathways. We show that many histidine kinases will accept ATPgammaS as a substrate to form a stable thiophosphohistidine even when they do not form stable phosphohistidines using the na ...[more]