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Vitamin D, the immune system and asthma.

ABSTRACT: The effects of vitamin D on bone metabolism and calcium homeostasis have long been recognized. Emerging evidence has implicated vitamin D as a critical regulator of immunity, playing a role in both the innate and cell-mediated immune systems. Vitamin D deficiency has been found to be associated with several immune-mediated diseases, susceptibility to infection and cancer. Recently, there has been increasing interest in the possible link between vitamin D and asthma. Further elucidation of the role of vitamin D in lung development and immune system function may hold profound implications for the prevention and treatment of asthma.

SUBMITTER: Lange NE

PROVIDER: S-EPMC2812815 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature

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Vitamin D, the immune system and asthma.

Lange Nancy E NE Litonjua Augusto A Hawrylowicz Catherine M CM Weiss Scott S

Expert review of clinical immunology 20091101 6

The effects of vitamin D on bone metabolism and calcium homeostasis have long been recognized. Emerging evidence has implicated vitamin D as a critical regulator of immunity, playing a role in both the innate and cell-mediated immune systems. Vitamin D deficiency has been found to be associated with several immune-mediated diseases, susceptibility to infection and cancer. Recently, there has been increasing interest in the possible link between vitamin D and asthma. Further elucidation of the ro ...[more]

PMID: 20161622

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