Ontology highlight
ABSTRACT:
SUBMITTER: Kebaier C
PROVIDER: S-EPMC2813373 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Kebaier Chahnaz C Vanderberg Jerome P JP
International journal for parasitology 20090803 1
Malaria infection is initiated when a mosquito injects Plasmodium sporozoites into a mammalian host. Sporozoites exhibit gliding motility both in vitro and in vivo. This motility is associated with the secretion of at least two proteins, circumsporozoite protein (CSP) and thrombospondin-related anonymous protein (TRAP). Both derive from micronemes, which are organelles that empty out of the apical end of the sporozoite. Sporozoite motility can be initiated in vitro by albumin added to the medium ...[more]