Characterizing dispersion in microfluidic channels.
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ABSTRACT:
SUBMITTER: Datta S
PROVIDER: S-EPMC2814782 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Publications
Characterizing dispersion in microfluidic channels.
Datta Subhra S Ghosal Sandip S
Lab on a chip 20090812 17
Dispersion or spreading of analyte bands is a barrier to achieving high resolution in microfluidic separations. The role of dispersion in separations is reviewed with emphasis on metrics, sources and common principles of analysis. Three sources of dispersion (a) inhomogeneous flow fields, (b) solute wall interactions and (c) force fields normal to channel walls are studied in detail. Microfluidic and nanofluidic applications to capillary electrophoresis, chromatography and field-flow fractionati ...[more]
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