Ontology highlight
ABSTRACT:
SUBMITTER: Tang S
PROVIDER: S-EPMC2826207 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Tang Shanwu S Presgraves Daven C DC
Science (New York, N.Y.) 20090201 5915
Speciation often involves the evolution of incompatible gene interactions that cause sterility or lethality in hybrids between populations. These so-called hybrid incompatibilities occur between two or more functionally divergent loci. We show that the nucleoporin 160kDa (Nup160) gene of the fruitfly Drosophila simulans is incompatible with one or more factors on the D. melanogaster X chromosome, causing hybrid lethality. Nup160 encodes a nuclear pore complex protein and shows evidence of adapti ...[more]