Ontology highlight
ABSTRACT:
SUBMITTER: Krasteva PV
PROVIDER: S-EPMC2828054 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Krasteva Petya V PV Fong Jiunn C N JC Shikuma Nicholas J NJ Beyhan Sinem S Navarro Marcos V A S MV Yildiz Fitnat H FH Sondermann Holger H
Science (New York, N.Y.) 20100201 5967
Microorganisms can switch from a planktonic, free-swimming life-style to a sessile, colonial state, called a biofilm, which confers resistance to environmental stress. Conversion between the motile and biofilm life-styles has been attributed to increased levels of the prokaryotic second messenger cyclic di-guanosine monophosphate (c-di-GMP), yet the signaling mechanisms mediating such a global switch are poorly understood. Here we show that the transcriptional regulator VpsT from Vibrio cholerae ...[more]