Ontology highlight
ABSTRACT:
SUBMITTER: Srivastava D
PROVIDER: S-EPMC3209240 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Srivastava Disha D Harris Rebecca C RC Waters Christopher M CM
Journal of bacteriology 20110916 22
Vibrio cholerae transitions between aquatic environmental reservoirs and infection in the gastrointestinal tracts of human hosts. The second-messenger molecule cyclic di-GMP (c-di-GMP) and quorum sensing (QS) are important signaling systems that enable V. cholerae to alternate between these distinct environments by controlling biofilm formation and virulence factor expression. Here we identify a conserved regulatory mechanism in V. cholerae that integrates c-di-GMP and QS to control the expressi ...[more]