Ontology highlight
ABSTRACT:
SUBMITTER: Watanabe H
PROVIDER: S-EPMC2828493 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
Addiction biology 20090701 3
The transcription factor DeltaFosB is accumulated in the addiction circuitry, including the orbitofrontal and medial prefrontal cortices of rodents chronically exposed to ethanol or other drugs of abuse, and has been suggested to play a direct role in addiction maintenance. To address this hypothesis in the context of substance dependence in humans, we compared the immunoreactivities of FOSB proteins in the orbitofrontal and dorsolateral prefrontal cortices (OFC and DLPFC respectively) between c ...[more]