Ontology highlight
ABSTRACT:
SUBMITTER: Meades G
PROVIDER: S-EPMC2831308 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Meades Glen G Benson Brian K BK Grove Anne A Waldrop Grover L GL
Nucleic acids research 20091203 4
Acetyl-CoA Carboxylase catalyzes the first committed step in fatty acid synthesis. Escherichia coli acetyl-CoA carboxylase is composed of biotin carboxylase, carboxyltransferase and biotin carboxyl carrier protein functions. The accA and accD genes that code for the alpha- and beta-subunits, respectively, are not in an operon, yet yield an alpha(2)beta(2) carboxyltransferase. Here, we report that carboxyltransferase regulates its own translation by binding the mRNA encoding its subunits. This in ...[more]