Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunity.
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ABSTRACT:
SUBMITTER: Rowe M
PROVIDER: S-EPMC2832755 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Publications
Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunity.
Microbes and infection 20100201 3
Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus-host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein-Barr virus, with particular emphasis on the molecular mechanisms of genes interfering with HLA class I antigen presentation. ...[more]
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