Ontology highlight
ABSTRACT:
SUBMITTER: Ohta K
PROVIDER: S-EPMC2833029 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Ohta Kazuhiro K Muramoto Kazumasa K Shinzawa-Itoh Kyoko K Yamashita Eiki E Yoshikawa Shinya S Tsukihara Tomitake T
Acta crystallographica. Section F, Structural biology and crystallization communications 20100223 Pt 3
The X-ray crystallographic structure of nitric oxide-treated bovine heart cytochrome c oxidase (CcO) in the fully reduced state has been determined at 50 K under light illumination. In this structure, nitric oxide (NO) is bound to the CcO oxygen-reduction site, which consists of haem and a Cu atom (the haem a(3)-Cu(B) site). Electron density for the NO molecule was observed close to Cu(B). The refined structure indicates that NO is bound to Cu(B) in a side-on manner. ...[more]