Ontology highlight
ABSTRACT:
SUBMITTER: Pines MK
PROVIDER: S-EPMC2834460 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Pines Mary K MK Housden Ben E BE Bernard Fred F Bray Sarah J SJ Röper Katja K
Development (Cambridge, England) 20100211 6
Gas2-like proteins harbour putative binding sites for both the actin and the microtubule cytoskeleton and could thus mediate crosstalk between these cytoskeletal systems. Family members are highly conserved in all metazoans but their in vivo role is not clear. The sole Drosophila Gas2-like gene, CG3973 (pigs), was recently identified as a transcriptional target of Notch signalling and might therefore link cell fate decisions through Notch activation directly to morphogenetic changes. We have gen ...[more]