Ontology highlight
ABSTRACT:
SUBMITTER: Johnson KR
PROVIDER: S-EPMC2836023 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Johnson Kenneth R KR Longo-Guess Chantal C Gagnon Leona H LH Yu Heping H Zheng Qing Yin QY
Genomics 20080815 4
The DBA/2J inbred strain of mice is used extensively in hearing research, yet little is known about the genetic basis for its early onset, progressive hearing loss. To map underlying genetic factors we analyzed recombinant inbred strains and linkage backcrosses. Analysis of 213 mice from 31 BXD recombinant inbred strains detected linkage of auditory brain-stem response thresholds with a locus on distal chromosome 11, which we designate ahl8. Analysis of 225 N2 mice from a backcross of (C57BL/6Jx ...[more]