Ontology highlight
ABSTRACT:
SUBMITTER: Meyer TE
PROVIDER: S-EPMC2837546 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Meyer Tamra E TE O'Brien Thomas G TG Andreotti Gabriella G Yu Kai K Li Qizhai Q Gao Yu-Tang YT Rashid Asif A Shen Ming-Chang MC Wang Bing-Sheng BS Han Tian-Quan TQ Zhang Bai-He BH Niwa Shelley S Fraumeni Joseph F JF Hsing Ann W AW
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20100303 3
Biliary tract cancers, encompassing cancers of the gallbladder, extrahepatic bile ducts, and ampulla of Vater, are rare but highly fatal. Gallstones represent the major risk factor for biliary tract cancer, and share with gallbladder cancer a female predominance and an association with reproductive factors and obesity. Although estrogens have been implicated in earlier studies of gallbladder cancer, there are no data on the role of androgens. Because intracellular androgen activity is mediated t ...[more]