Increased fetal cell trafficking in murine lung following complete pregnancy loss from exposure to lipopolysaccharide.
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ABSTRACT:
SUBMITTER: Johnson KL
PROVIDER: S-EPMC2842077 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
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Increased fetal cell trafficking in murine lung following complete pregnancy loss from exposure to lipopolysaccharide.
Johnson Kirby L KL Tao Kai K Stroh Helene H Kallenbach Lisa L Peter Inga I Richey Lauren L Rust Daniel D Bianchi Diana W DW
Fertility and sterility 20091007 5
To determine whether chemically induced miscarriage affects fetomaternal trafficking in a mouse model, we measured the amount of fetal DNA present in various maternal organs by polymerase chain reaction amplification following exposure to lipopolysaccharide (LPS). As the frequency of fetal cells and the number of animals with detectable microchimerism following LPS injection were significantly increased, particularly in lung tissue compared to controls, with no signs of an inflammatory response, ...[more]
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