Ontology highlight
ABSTRACT:
SUBMITTER: Yang J
PROVIDER: S-EPMC2844961 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Yang Jie J Chen Rui R Wei Junxia J Zhang Fanglin F Zhang Yong Y Jia Lintao L Yan Yan Y Luo Wen W Cao Yunxin Y Yao Libo L Sun Jifeng J Xu Zhikai Z Yang Angang A
Applied microbiology and biotechnology 20091210 4
Hantaan virus (HTNV) is the type of Hantavirus causing hemorrhagic fever with renal syndrome, for which no specific therapeutics are available so far. Cell type-specific internalizing antibodies can be used to deliver therapeutics intracellularly to target cell and thus, have potential application in anti-HTNV infection. To achieve intracellular delivery of therapeutics, it is necessary to obtain antibodies that demonstrate sufficient cell type-specific binding, internalizing, and desired cellul ...[more]